MetaPath Online

MetaPath Online

Determination of the order in which product-metabolites are produced when a metabolic network is feeded with the seed [read more...] The algorithm calculating a scope of a predefined seed in a given network works in an iterative manner, as described in the description of the "scope" function. The iteration step in which a particular product-metabolite is incorporateted can be used to define its metabolic proximity to the seed. Also, it can be analysed whether particular metabolites only enable the production of further metabolites. [<< hide]
Reaction Set:	User defined reaction set (Rxxxxx,Ryyyyy,...): Irreversibility Cofactor functionality: ATP/ADPNAD/NADH NADP/NADPHCoA	Select the reaction set on which the scope calculation will be performed. "Irreversibility" defines whether irreversible reactions can only be traversed in forward direction. When selecting "cofactor functionalities", reactions depending on certain cofactors can operate also without them. The algorithms ensure that no compounds are synthesized from the cofactors itself.

Seed:	atp;h2o	Enter the initial substrates which will be used for synthesizing all the other compounds of the scope. Enter metabolite names separated by ";".

Output:	Link to KEGG database	Compound and Reaction IDs will be linked to the corresponding entries in KEGG.